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Portable Rat Stereotaxic Surgery Frame

Instead of a U-frame design, this instrument utilises adaptors to enlarge operating space thus offering additional working space for surgical instruments when working on the rat brain.

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Instead of a U-frame design, this instrument utilises adaptors to enlarge operating space thus offering additional working space for surgical instruments when working on the rat brain. The Stereotaxic Instrument includes 3-axes, a left-hand manipulator arm, rat adaptor, rat 18 ° ear bars, and a standard probe holder. Multiple subassembly options are available such as dual-arm, digital, etc.

Technical Parameters

  1. Base plate size: 400mm x 255mm.
  2. Distance between ear bar and base plate: 35.5mm.
  3. Ear bar slots with vernier of 0.1mm resolution.
  4. Scale range of Ear bars: 35mm with 1mm resolution.
  5. Dorsal/Ventral adjustment range for the adaptor: 30mm (+10mm~-20mm) with 0.1mm resolution.
  6. Working distance in 3 dimension is 80 mm with precise alignment to 0.1mm resolution.
  7. Vertical direction: 180° rotation and lock at any angles.
  8. Horizontal direction: 360° rotation and lock at any angles.
  9. Dual-lead screws ensure stable, accurate and smooth manipulation.
  10. Accuracy and flexibility can be maintained at variable temperatures.
  11. Unique anti-clockwise UP mark engraved in the knob prevents incorrect operation.
  12. Vertical lock and fixing knob are separated to ensure accurate function at any angle.
  13. Replacing the U-frame enlarges the operating space, also making it more economical and reliable
  14. Laser engraved scales enable comfortable reading.
  15. Ear bar locked plate pressing instead of clamping ensures more stability.
  16. Syringe pump, micro camera and drill can be attached to instruments.

 

Model Information

 Model

Product Description

Adaptor

Ear bar

Three-dimensional manipulator

Holder

Base plate

68505

Stereotaxic for Rat

68021

18°

SGL-Left

68201

68864S

68508

Stereotaxic for Rat

68021

18°

Dual

68201

68864D

68511

Stereotaxic for Rat

68021

18°

Digital, SGL-Left

68201

68864S

68514

Stereotaxic for Rat

68021

18°

Digital, Dual

68201

68864D

 

References

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Fan, X. C., Fu, S., Liu, F. Y., Cui, S., Yi, M., & Wan, Y. (2018). Hypersensitivity of prelimbic cortex neurons contributes to aggravated nociceptive responses in rats with experience of chronic inflammatory pain. Frontiers in molecular neuroscience, 11, 85.

Liu, Y., Lai, S., Ma, W., Ke, W., Zhang, C., Liu, S., … & Shu, Y. (2017). CDYL suppresses epileptogenesis in mice through repression of axonal Nav1. 6 sodium channel expression. Nature communications, 8(1), 1-17.

Tang, Y., Lin, Y. H., Ni, H. Y., Dong, J., Yuan, H. J., Zhang, Y., … & Chang, L. (2017). Inhibiting Histone Deacetylase 2 (HDAC 2) Promotes Functional Recovery From Stroke. Journal of the American Heart Association, 6(10), e007236.

Huang, L., Yuan, T., Tan, M., Xi, Y., Hu, Y., Tao, Q., … & Luo, M. (2017). A retinoraphe projection regulates serotonergic activity and looming-evoked defensive behaviour. Nature communications, 8(1), 1-13.

Zhu, M., Li, H., Gyanwali, B., He, G., Qi, C., Yang, X., … & Tang, A. (2017). Auditory brainstem responses after electrolytic lesions in bilateral subdivisions of the medial geniculate body of tree shrews. Neurological Sciences, 38(9), 1617-1628.

Lei, Z., Wang, D., Chen, N., Ma, K., Lu, W., Song, Z., … & Wang, J. H. (2017). Synapse innervation and associative memory cell are recruited for integrative storage of whisker and odor signals in the barrel cortex through miRNA-mediated processes. Frontiers in cellular neuroscience, 11, 316.

Zhou, H., Xiong, G. J., Jing, L., Song, N. N., Pu, D. L., Tang, X., … & Richter-Levin, G. (2017). The interhemispheric CA1 circuit governs rapid generalisation but not fear memory. Nature communications, 8(1), 1-10.

Zhang, J., Liu, H., Du, X., Guo, Y., Chen, X., Wang, S., … & Zhang, W. (2017). Increasing of blood-brain tumor barrier permeability through transcellular and paracellular pathways by microbubble-enhanced diagnostic ultrasound in a C6 glioma model. Frontiers in neuroscience, 11, 86.

Li, G. F., Zhao, H. X., Zhou, H., Yan, F., Wang, J. Y., Xu, C. X., … & Zhang, H. L. (2016). Improved anatomical specificity of non-invasive neuro-stimulation by high frequency (5 MHz) ultrasound. Scientific reports, 6(1), 1-11.

Liu, M. G., Li, H. S., Li, W. G., Wu, Y. J., Deng, S. N., Huang, C., … & Xu, T. L. (2016). Acid-sensing ion channel 1a contributes to hippocampal LTP inducibility through multiple mechanisms. Scientific reports, 6, 23350.

Zhao, Baisong, et al. “Hyperbaric oxygen pretreatment improves cognition and reduces hippocampal damage via p38 mitogen-activated protein kinase in a rat model.” Yonsei medical journal 58.1 (2017): 131-138.

Zhao, Yunan, et al. “Decreased glycogen content might contribute to chronic stress-induced atrophy of hippocampal astrocyte volume and depression-like behavior in rats.” Scientific reports 7 (2017): 43192.

Espinosa, P., Silva, R. A., Sanguinetti, N. K., Venegas, F. C., Riquelme, R., González, L. F., … & Sotomayor-Zárate, R. (2016). Programming of dopaminergic neurons by neonatal sex hormone exposure: effects on dopamine content and tyrosine hydroxylase expression in adult male rats. Neural plasticity, 2016.

Li, Wei-Guang, et al. “ASIC1a regulates insular long-term depression and is required for the extinction of conditioned taste aversion.” Nature communications 7.1 (2016): 1-15.

Wang, G. Q., Cen, C., Li, C., Cao, S., Wang, N., Zhou, Z., … & Wang, J. (2015). Deactivation of excitatory neurons in the prelimbic cortex via Cdk5 promotes pain sensation and anxiety. Nature communications, 6(1), 1-16.

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