Head Nose Only Units

Head Nose Only Units

Modular Expandable Design

TSE Systems Head Nose Only exposure units have a modular expandable design which allows them to be continually adapted to the customer’s requirements. The structure consists of single segments that can be stacked on top of each other.

Each Head Nose Only exposure unit can be equipped with the required aerosol inlet interfaces, appropriate exposure tubes, various sampling ports, and environmental sensor connections. The restrainer construction is designed for simple operation, quick replacement and easy cleaning, for a wide range of species – mouse up to guinea pig size is standard. Special exposure units for dog inhalation studies can also be provided.

The Head Nose Only Units have a directed-flow design, i.e. there is minimal rebreathing of expired air. The test atmosphere flows into an inner plenum that directs the flow towards the nose or head of each test animal. The exhaled air is then discarded along with the excess airflow into an outer plenum.

Depending on the laboratory requirements, the units are customized for use in fume hoods or as mobile units on casters with brakes.

Features

• Modular expandable design
• Sample ports for taking samples directly from the spot where an animal’s nose is located
• Excrement tray for easy collection and disposal of animal feces – easy to clean
• Units are customized for use in fume hoods or as mobile units on casters with brakes

Selected Publications

Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System (2017) – Jonathan E. Phillips, Xuxia Zhang, James A. Johnston

Selected Product Citations